Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1975-02-18
1976-06-08
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Lymphokine
424 86, A61K 3912, A61K 3942
Patent
active
039624226
ABSTRACT:
Method for immunizing nursing piglets against transmissible gastroenteritis (TGE) virus by administering to the pregnant sow an effective amount of a vaccine containing attenuated TGE virus and permitting the nursing piglets to suckle the sow. The vaccine is administered twice, (a) intramuscularly at from about 63 days to about 21 days pre-farrowing and (b) intranasally at from about 21 days to about 7 days pre-farrowing, with the proviso that at least 14 days and not more than 42 days elapse between the intranasal and intramuscular inoculations.
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bohl, E. H. et al., Infection & Immunity 6 (3): 289-301 (Sept. 1972) "Antibody Responses in Serum, Colostrum and Milk of Swine After Infection or Vaccination with Transmissible Gastroentoritis Virus".
Saif, L. J. et al., Infection & Immunity 6 (4) : 600-609 (Oct. 1972) "Isolation of Porcine Immunoglobulins and Determination of the Immunoglobulin Classes of Transmissible Gastroentoritis Viral Antibodies".
Benyeda, J. et al., Vet. Bull. 44 (8) No. 3735, Aug. 1974 "Immunization Against Transmissible Gastroenteritis II, Persistence of Antibody and Effect of Revaccination".
Mocsari, E. et al., Vet. Bull. 44 (12) No. 5954, Dec. 1974 "Immunization Against Transmissible Gastroenteritis IV, Antibody Formation in Sows Immunized Twice".
Blaufarb Gerard A.
Rose Shep K.
Syntex (U.S.A.) Inc.
Walker William B.
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