Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1996-08-13
1998-11-03
Railey, II, Johnny F.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
4351723, 4352351, 435325, 435349, 435373, C12N 510, C12N 702, C12N 1563, C12N 1586
Patent
active
058307230
ABSTRACT:
This invention relates to the introduction of p53 under the control of the metallothionein promoter into primary cells to produce immortalized cell lines. The cells are useful as substrates for viral propagation, as contaminant-free sources for recombinant protein production, for recombinant virus production and as cell substrates to support primary cells and improve virus yield during virus propagation.
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Farris James A.
Foster Douglas N.
Foster Linda K.
Railey II Johnny F.
Regents of the University of Minnesota
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