Method for imaging mammalian tissue using 1-substituted- 4,7,10-

Details Method for imaging mammalian tissue using 1-substituted- 4,7,10- Method for imaging mammalian tissue using 1-substituted- 4,7,10-

1995-06-06

1997-10-07

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

514184, 514836, 540465, 540467, 436173, A61B 5055

Patent

active

056744706

ABSTRACT:
A method for imaging mammalian tissue utilizing a non-ionic complex of a paramagnetic ion of lanthanide element and a macrocyclic chelating agent.

REFERENCES:
patent: 4639365 (1987-01-01), Sherry et al.
patent: 4647447 (1987-03-01), Gries et al.
patent: 4678667 (1987-07-01), Meares et al.
patent: 4719098 (1988-01-01), Weinmann et al.
patent: 4804529 (1989-02-01), Bardy et al.
patent: 4826673 (1989-05-01), Dean et al.
patent: 4885363 (1989-12-01), Tweedle et al.
patent: 4957939 (1990-09-01), Gries et al.
patent: 4963344 (1990-10-01), Gries et al.
Atkins et. al., "Macrocyclic polyamines: 1,4,7,10,13,16-Hexaazacyclooctadecane," vol. 58, p. 86, (1978). Publisher John Wiley and Sons.
XVI International Congress of Radiology, Hawaii, USA - Jul. 8-12, 1985; New Nonionic Structures for X-Ray and MRI Contrast Agents; H. Gries, et. al.
J. Amer. Chem. Soc. vol. 96 (1974), p. 2268, J.E. Richman, T. Atkins, "Nitrogen Analogs of Crown Ethers".
Angew. Chem. Int. Ed., vol. 15, 1976, p. 686, "Complex Formation with Tetraazacycloalkane-N,N', N', N'-tetraacetic Acids as function of Ring Size", H. Stetter, W. Frank.
Talantu, vol. 29, p. 815, "Metal Complexes of Cyclic Tetra-Azatetra-Acetic Acids", R. Delgaix, J. Frausto DaSilva (1982).
Inorg. Chem. vol. 19, 1980 p. 1319, "Nuclear Magnetic Resonance Spectroscopy of Lanthanide Complexes with a Tetraacetic Tetraaza Macrocycle Unusual Conformation Properties", J.F. Desreux.
Inorg. Chem. vol. 23, 1984, p. 4459, "Luminescence and NMR Studies Conformational Isomers of Lanthanide Complexes with an Optically Active Polyaza Polycarboxylic Macrocycle", H. Brittain, J. Desreux.
Tetrahedron, vol. 37, (1981) p. 767, "Darstellung Und Komplexbildung Von Polyazacycloalkan-N-Essigsauren", H. Stetter, W. Frank, R. Mertens (Abstract only).
Society of Magnetic Resonance in Medicine; Fifth Annual Meeting Aug. 19-22, 1986, Montreal, Quebec Canada. "Progress Toward Development of Neutral NMR Contrast".
Agents, D.A. Place, A.V. Kramer, J.B. Aguayo, T.K. Natarajan, J.H. Anderson, J.M. Vachino Bonnemain et. al., Chem. Abst. 108-137926Z (1988).
R.M. Kniseley et. al., "Delineation of Active Marrow by Whole-Body Scanning with Radioactive Colloids", J. of Nucl. Med., 7:575-582, 1966.
C.A. Chang et al., JMRI vol. 2, No. 1, pp. 95-98 (1992).
M.F. Tweedle et al., Radiol., vol. 178, No. 3, 891 (1991).
G. Gaughan, "Nonionic Gadolinium Chelates", Enhanced Magnetics Resonance Imaging edited by Val M. Runge, pp. 105-116 (1989).
C. Geraldes et. al., "Nuclear Magnetic Resonance and Potentiometric Studies of the Protonation Scheme of a Triaza Triacetic Macrocycle and Its Complexes with Lanthanum and Lutetium", Inorg. Chem., vol. 24, No. 23, pp. 3876-3881 (1985).
R.H. Knop et. al., "Gadolinium Cryptates as a new class of water soluble MRI contrast agents: Comparison to GD-DTPA for organ and pathology localization", Soc. Magn. Reson., Abstracts, 871-872, Aug. 19, 1985.

Affiliated with

Also associated with

Rating

Method for imaging mammalian tissue using 1-substituted- 4,7,10- does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for imaging mammalian tissue using 1-substituted- 4,7,10-, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for imaging mammalian tissue using 1-substituted- 4,7,10- will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2354357