Method for imaging mammalian tissue using 1-substituted-1,4,7-tr

Details Method for imaging mammalian tissue using 1-substituted-1,4,7-tr Method for imaging mammalian tissue using 1-substituted-1,4,7-tr

1994-12-20

1995-12-12

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

514184, 514836, 1286534, 436173, 436806, 540465, 540467, A61B 5055

Patent

active

054747562

ABSTRACT:
A method for imaging mammalian tissue utilizing a non-ionic complex of a paramagnetic ion of lanthanide element and a macrocyclic chelating agent.

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C. Geraldes et al., "Nuclear Magnetic Resonance and Potentiometric Studies of the Protonation Scheme of a Triaza Triacetic Macrocycle and Its Complexes with Lanthanum and Lutetium", Inorg. Chem., 1985, 24, 3876-3881.
R. H. Knop et al., "Gadolinium Cyrptates as a new class of water soluble MRI contrast agents: Comparison to GD-DTPA for organ and pathology localization", Soc. Magn. Reson., Abstracts, 871-872, Aug. 19, 1985.
R. M. Kniseley et al., "Delineation of Active Marrow by Whole-Body Scanning with Radioactive Colloids", J. of Nucl. Med., 7:575-582, 1966.
H. Gries, et al., New Nonionic Structures for X-ray and MRI Contrast. 16th International Congress of Radiology (1989).

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