Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system
Reexamination Certificate
2007-08-14
2007-08-14
Arana, Louis M. (Department: 2859)
Electricity: measuring and testing
Particle precession resonance
Using a nuclear resonance spectrometer system
C324S309000
Reexamination Certificate
active
10997209
ABSTRACT:
The present invention includes a method for MR imaging of a biological matter having H2O17content by performing T1ρoffimaging of said H2O17content in said biological matter. The T1ρoffimaging is performed by applying an RF pulse with a resonance frequency offset to said biological matter to create off resonance spin locking conditions in said biological matter. Thus, parts of the biological matter having different H2O17concentrations are differentiated because of their different T2/T1 ratios.
REFERENCES:
patent: 5588431 (1996-12-01), Mani et al.
patent: 6265875 (2001-07-01), Saranathan et al.
patent: 6294914 (2001-09-01), Fiat
patent: 6313631 (2001-11-01), Fiat et al.
patent: 6486668 (2002-11-01), Ma
Arai, Toshiyuki et al., “Measurement of Local Cerebral Blood Flow by Magnetic Resonance Imaging: In Vivo Autoradiographic Strategy Using17O-Labeled Water”, Elsevier Science Inc., Brain Research Bulletin, vol. 45, (1998) pp. 451-456.
Charagundla, Sridhar R., et al., “Off-Resonance Proton T1pDispersion Imaging of17O-enriched Tissue Phantoms”, Magnetic Resonance in Medicine, vol. 39, (1998) pp. 588-595.
de Crespigny, A.J. et al., “MRI of Focal Cerebral Ischemia Using17O-Labeled Water”, Magnetic Resonance in Medicine, vol. 43, (2000) pp. 876-883.
Fiat, D., et al., “In Vivo17O NMR Study of Rat Brain During17O2Inhalation”, Magnetic Resonance in Medicine, vol. 24, (1992) pp. 370-374.
Hopkins, Amos L. et al., “Oxygen-17 contrast Agents Fast Imaging Techniques”, Investigative Radiology, vol. 23, Suppl. 1, (1988) pp. S240-S242.
Moran, Paul R. et al., “Near-Resonance Spin-Lock Contrast”, Elsevier Science Inc., Magnetic Resonance Imaging, vol. 13, No. 6, (1995) pp. 837-846.
Pekar, J., et al., “In Vivo Measurement of Cerebral Oxygen Consumption and Blood Flow Using17O Magnetic Resonance Imaging”, Academic Press, Inc., Magnetic Resonance in Medicine, vol. 21, (1991) pp. 313-319.
Pike, G. Bruce et al., “In Pulsed Magnetization Transfer Spin-Echo MR Imaging”, Journal of Magnetic Resonance Imaging, vol. 3, No. 3 (1993) pp. 1-6.
Reddy, Ravinder et al., “17O-Decoupled1H Detection Using a Double-Tuned Coil”, Elsevier Science Inc., Magnetic Resonance Imaging, vol. 14, No. 9 (1996) pp. 1073-1078.
Rizi, Rahim R. et al., “Proton T1p-Dispersion Imaging of Rodent Brain at 1.9T”, Journal Metabolic Magnetic Resonance and Computing Center, vol. 8, No. 5, (1998) pp. 1090-1096.
Wolff, Steven D., et al., “Magnetization Transfer Contrast(MTC)and Tissue Water Proton Relazation in Vivo”, Magnetic Resonance in Medicine, vol. 10, (1989) pp. 135-144.
Arana Louis M.
Dorsey & Whitney LLP
The Board of Trustees of the Leland Stanford Junior University
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