Method for identifying T cells involved in autoimmune disease

Details Method for identifying T cells involved in autoimmune disease Method for identifying T cells involved in autoimmune disease

1993-12-20

1998-07-07

Saunders, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 6, 436501, 436506, 436509, 436548, C12Q 168, G01N 33564

Patent

active

057767084

ABSTRACT:
The invention relates to a method for identifying T cell populations involved in autoimmune diseases. This involves determining levels of a V.beta. element in a body fluid sample of a patient and comparing this to normal levels. Variation from normal levels is indicative of an autoimmune disease. The invention also involves assaying T cell subpopulations in a sample to determine clonality of .beta. chains. Clonality can also be used to diagnose autoimmune disorders.

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