Method for identifying T cells disease involved in autoimmune di

Details Method for identifying T cells disease involved in autoimmune di Method for identifying T cells disease involved in autoimmune di

1991-07-18

1994-03-29

Saunders, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

424 9, 435 6, 436506, 436509, G01N 33564

Patent

active

052983960

ABSTRACT:
The invention relates to a method for identifying T cell populations involved in autoimmune diseases. This involves determining levels of a V.beta. element in a body fluid sample of a patient and comparing this to normal levels. Variation from normal levels is indicative of an autoimmune disease. The invention also involves assaying T cell subpopulations in a sample to determine clonality of .beta. chains. Clonality can also be used to diagnose autoimmune disorders.

REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4886743 (1989-12-01), Hood et al.
M. Chatila et al, Jour. Cell. Biochem. Suppl. 15 (Part E), 162, 1991.
M. D. Howell et al, Biol. Abstr., 93, Abstr. No. 49037, 1991.
B. Kotzin et al, Jour. Cell. Biochem. Suppl. 15 (Part E), 144, 1991.
H. Acha-Orbea et al, Cell, 54, 263-273, 1988.
A. Sottini et al, Europ. Jour. Immunol., 21, 461-466, 1991.

Affiliated with

Also associated with

Rating

Method for identifying T cells disease involved in autoimmune di does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for identifying T cells disease involved in autoimmune di, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for identifying T cells disease involved in autoimmune di will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-790843