Method for identifying potential contrast media reactors

Details Method for identifying potential contrast media reactors Method for identifying potential contrast media reactors

1980-07-10

1982-06-15

Hruskoci, Peter A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435810, 424 5, C12Q 138

Patent

active

043352030

ABSTRACT:
Method and kit are provided for determining hypersensitivity, particularly to polyiodinated contrast media. Plasma is combined with a prekallikrein activator and a substrate capable of providing a detectible signal and the proteolytic activity measured by determining the signal level by means of the transformation of said substrate.

REFERENCES:
patent: 3404143 (1968-10-01), Hebky et al.
patent: 4038147 (1977-07-01), Reno
patent: 4252902 (1981-02-01), Fujii et al.
Kluft, "Determination of Prekallikrein in Human Plasma:" J. Lab. Clin. Med. Jan. 1978, pp. 83-95.
Stormorken et al., Haemostasis, 1978, 7: 69-75.
Gjonnaess, Haemorrn, 1972, 28: 182-193.
Griffin et al., Seminars in Thrombosis & Hemostasis, 5: 54-273; 1979.

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