Method for identifying peptides in a biological sample

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification

Reexamination Certificate

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C514S001100, C424S001690

Reexamination Certificate

active

07906630

ABSTRACT:
The invention provides a method for isolating a cargo peptide from a sample containing a cargo peptide-carrier protein complex. The method involves contacting a sample comprising a cargo peptide-carrier protein complex with a binding moiety selective for the carrier protein, under conditions wherein the carrier protein binds non-covalently to the binding moiety, and wherein the binding moiety is attached to a support, dissociating the cargo peptide from the cargo peptide-carrier protein complex, wherein the carrier protein remains bound to the binding moiety, and collecting the cargo peptide, whereby the cargo peptide is isolated from the sample.

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