Multicellular living organisms and unmodified parts thereof and – Method of making a transgenic nonhuman animal – Involving breeding to produce a double transgenic nonhuman...
Reexamination Certificate
2005-09-27
2005-09-27
Woitach, Joseph (Department: 1632)
Multicellular living organisms and unmodified parts thereof and
Method of making a transgenic nonhuman animal
Involving breeding to produce a double transgenic nonhuman...
C800S003000, C800S008000, C800S009000, C800S010000, C800S021000
Reexamination Certificate
active
06949692
ABSTRACT:
Methods for breeding mutagenized mice permit detection of genetic loci that in heterozygous mutated form can modify a known index phenotype involves crossing a mutagenized founder strain and a second strain of mice carrying an allele at a locus that confers the index phenotype. In the test generation, clusters of individuals are observed to deviate from the typical phenotype. The genetic material and molecules encoded thereby can be obtained using available methods. Improved and compact methods are also disclosed.
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Dove William F.
Shedlovsky Alexandra
Quarles & Brady LLP
Wisconsin Alumni Research Foundation
Woitach Joseph
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