Method for identifying genes involved in cell proliferation

Details Method for identifying genes involved in cell proliferation Method for identifying genes involved in cell proliferation

2005-09-13

2005-09-13

Li, Q. Janice (Department: 1632)

Chemistry: molecular biology and microbiology

Process of mutation, cell fusion, or genetic modification

C435S006120, C435S007100, C435S008000, C800S008000, C800S009000, C800S010000, C800S013000, C800S020000, C800S021000, C800S022000

Reexamination Certificate

active

06943025

ABSTRACT:
The present invention provides fish system as a powerful forward genetic tool to directly identify a number of novel genes involved in cell proliferation in vertebrates without the time consuming and costly maintenance of animals. The invention provides a tool to identify functional characteristics of a protein without prior knowledge of the gene sequence. After identification of the mutant gene in the fish system, the nucleic acid sequence of the gene can be used for identifying a homologue of the gene in another species, for example, in humans.

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