Method for identifying anti-nematode compounds

Details Method for identifying anti-nematode compounds Method for identifying anti-nematode compounds

1995-05-26

1998-10-13

Walsh, Stephen

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Isomerase

435 71, 435174, C12Q 1533, C12N 1202

Patent

active

058211071

ABSTRACT:
The present invention relates to the use of these cyclophilins, hereinafter referred to as "cyclophilin-like proteins (CLP)" in a method for identifying compounds capable of binding to and/or inhibiting the enzymatic activity of these proteins. Such compounds may be further screened for their ability to inhibit parasites which are not susceptible to the anti-parasitic effects of CsA.

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