Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-06-07
1998-07-07
Feisee, Lila
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 72, 435325, 435374, G01N 3353, C12N 506
Patent
active
057767076
ABSTRACT:
Cells expressing Leukocyte Adhesion Molecule-1 (LAM-1) are identified by reaction with an anti-LAM1-3 monoclonal antibody produced by a hybridoma cell line made by the fusion of NS-1 myeloma cells with spleen cells obtained from mice immunized with a LAM-1 cDNA transfected cells. The identification methods are expected to be clinically useful in the diagnosis of disease such as AIDS, which are associated with cells expressing LAM-1 surface protein.
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T.F. Tedder et al.; "Human antigen-specific memeory T cells express homing Receptor (LAM-1) . . . ," Eur. J. Immunol., 20: 1351-1355 (1990).
T.F. Tedder et al., "Expression of The Human Leukocyte Adhesion Molecule, LAM-1," J. Immunol., 144: 532-540 (1990).
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Spertini Olivier G.
Tedder Thomas F.
Dana-Farber Cancer Institute
Feisee Lila
Gambel Phillip
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