Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2011-04-05
2011-04-05
Noakes, Suzanne M (Department: 1656)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C702S019000, C702S027000
Reexamination Certificate
active
07919267
ABSTRACT:
The present invention related to a method for crystallizing a CMY-10 being a β-lactamase with extended-substrate spectrum, a crystal of CMY-10, and a crystal structure of CMY-10. With utilization of three-dimensional structure of CMY-10 protein provided by the present invention, it is possible to develop novel antibiotics or inhibitors that can prevent an emergence of resistance bacteria appeared by plasmidic class C β-lactamases having extended-substrate specificity.
REFERENCES:
Sun-Joo Lee et al.; “Crystallization and preliminary X-ray crystallographic analyses of CMY-1 and CMY-10, plasmidic class C beta-lactamases with extended substrate spectrum”, In: acta Crystallographica; Feb. 2, 2004; D60; pp. 382-384.
Cha Sun-Shin
Jung Ha-Il
Lee Jung-Hun
Lee Sang-Hee
Edwards Angell Palmer & & Dodge LLP
Kim Kongsik
Lee Jae W
Lee Sang-Hee
Myongji University Industry and Academia Cooperation
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