Method for identifying a target peptide that modulates the bindi

Details Method for identifying a target peptide that modulates the bindi Method for identifying a target peptide that modulates the bindi

1996-05-06

1998-11-03

Eisenschenk, Frank C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 71, 435 72, 530395, G01N 3353, G01N 33555, C07K 1400, C07K 1700

Patent

active

058306781

ABSTRACT:
A substantially pure epinectin covalently linked glycoprotein complex is disclosed having a ligand portion binding at least to the .alpha..sub.3 .beta..sub.1 integrin receptor for use in modifying cellular adhesion to a substratum. Also disclosed are specific binding partners for epinectin, as exemplified by monoclonal antibody, and .alpha..sub.3 .beta..sub.1 and .alpha..sub.6 .beta..sub.4 integrin receptor peptides for use as inhibitors, antagonists, and agonists of receptor binding to epinectin ligand.

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