Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase
Patent
1992-01-21
1993-10-05
Wityshyn, Michael G.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving transferase
435 25, 435 90, 435188, C12Q 148, C12Q 126, C12P 1936, C12N 996
Patent
active
052504166
ABSTRACT:
The present invention relates to a method for determining a slight amount of NADH or XTP which is present in a solution, with high sensitivity by the use of an NADH kinase specific for NADH by utilizing a cycling reaction, and this method permits highly sensitive determination of NADH without any influence of NAD.sup.+ and hence is useful for diagnoses of diseases and the like.
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Iwahashi, et al., "Localization of the NADH Kinase in the Inner Membrane of Yeast Mitochondria", J. Biochem., 105:916-921 (1989).
Iwahashi, et al., "Characterization of NADH Kinase from Saccharomyces cerevisiae", J. Biochem. 105:588-693 (1989).
Iwahashi, et al., "Orientation and Reactivity of NADH Kinase in Proteoliposomes", J. Biochem., 105:922-926 (1989).
World Patents Index Latest Weeek 9232, Derwent Publications Ltd., London, BG; AN92-260430 & DE-A-4 201 930 (Noda Inst Sci Res) Jul. 30, 1992, Abstract
Horiuchi Tatsuo
Kishi Koji
Ohno Tsuyoshi
Shirahase Yasushi
Suzuki Masaru
Gitomer Ralph G.
International Reagents Corp.
Noda Institute for Scientific Rsearch
Wityshyn Michael G.
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