Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Free from infectious agents
Reexamination Certificate
2006-10-24
2006-10-24
Chan, Christina (Department: 1644)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Free from infectious agents
C424S177100, C530S390100
Reexamination Certificate
active
07125552
ABSTRACT:
The method for immune serum globulin purification relates to the purification of immune globulins from blood plasma with a high degree of efficiency and a high rate of recovery. The immune globulin source is Cohn's fraction I+II+III or II+III prepared from plasma or plasma intermediates by precipitation of the paste at pH 6.7 to 6.8 in the presence of 20% ethanol and 80% purified water. A glycine extraction is followed by an anion exchange chromatography column step to achieve a significantly high yield and high purity of the concentrated protein.
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K. Tanaka, E. Sawtani, G. A. Dias, E. M. Shigueoka, T.C.X.B. Campos, H.C. Nakao and F. Arashiro, “High Quality Human Immunoglobulin G Purified from Cohn Franctions by Liquid Chromatography.” Brazilian Journal of Medical and Biological Research, Jan. 2000, vol. 33, No. 1, pp. 27-30, Sao Paulo, SP, Brasil.
Levy Joshua
Rothstein Fred
Shimiaei Bahman
Chan Christina
Hemacare Corporation
Kim Yunsoo
LandOfFree
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