Chemistry: analytical and immunological testing – Measurement includes temperature change of the material...
Reexamination Certificate
2003-11-21
2008-08-26
Sines, Brian J (Department: 1797)
Chemistry: analytical and immunological testing
Measurement includes temperature change of the material...
C422S050000, C422S051000, C422S068100, C422S082120, C436S043000, C436S174000, C436S175000, C436S180000, C374S031000, C374S032000
Reexamination Certificate
active
07416897
ABSTRACT:
A method is disclosed for high-throughput screening assay sample preparation and testing for the identification of binding between drug targets and library compounds, for use with a calorimetric device measuring the enthalpy of reaction for the binding. The method includes mixing a library compound with a specified solvent and mixing a target compound solution with a second specified solvent on a calorimetric device. The library compound/solvent is merged with the target compound/solvent solution and the library compound/solvent solution is also merged with a third solvent solution on the calorimetric device. The heats of reaction are detected for both merged solutions and are compared.
REFERENCES:
patent: 5942443 (1999-08-01), Parce et al.
patent: 6294063 (2001-09-01), Becker et al.
patent: 6380605 (2002-04-01), Verhaegen
patent: 6545334 (2003-04-01), Verhaegen
patent: 2004/0038227 (2004-02-01), Verwaerde et al.
patent: 2005/0076943 (2005-04-01), Cooper et al.
Lehto et al. (WO 99/54730).
U.S. Appl. No. 09/946,047, filed Sep. 4, 2001, Connelly et al.
U.S. Appl. No. 10/114,611, filed Apr. 1, 2002, Bell et al.
U.S. Appl. No. 10/115,336, filed Apr. 1, 2002, Elrod et al.
U.S. Appl. No. 10/159,606, filed May 31, 2002, Chow et al.
U.S. Appl. No. 10/303,446, filed Nov. 22, 2002, Bruce et al.
U.S. Appl. No. 10/303,500, filed Nov. 22, 2002, Bruce et al.
R. Seethala, P.B. Fernandes, eds, Handbook of Drug Screening, Marcel Dekker Inc., 2001.
Bell Alan G.
Bruce Richard H.
Peeters Eric
Torres Francisco E.
Fay Sharpe LLP
Palo Alto Research Center Incorporated
Sines Brian J
LandOfFree
Method for high-throughput screening assay sample... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for high-throughput screening assay sample..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for high-throughput screening assay sample... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4014744