Method for high throughput cell-based assays using versatile...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S287100, C435S289100

Reexamination Certificate

active

07419778

ABSTRACT:
The present invention relates to methods for screening of cellular responses of cellular components comprising: (a) providing cellular components on the surface of a substrate, said substrate having immobilized thereon an array of detector molecules; (b) delivering test compounds to positions on the substrate corresponding to the arrayed detector molecules on the surface of said solid substrate; (c) incubating said test compounds with said cellular components on the surface of the solid support, under conditions allowing the induction of cellular responses; (d) assaying said cellular responses; and, identifying and characterizing the cellular responses induced by said test compounds. The present invention further relates to the uses of said methods as well as microarrays and kits for carrying out said methods.

REFERENCES:
patent: 6103479 (2000-08-01), Taylor
patent: 6197575 (2001-03-01), Tannenbaum et al.
patent: 6225131 (2001-05-01), van Damme et al.
patent: 2002/0072116 (2002-06-01), Bhatia et al.
patent: 2007/0072187 (2007-03-01), Blok et al.
patent: WO 98/38490 (1998-09-01), None
patent: WO 99 02266 (1999-01-01), None
patent: WO 00 31304 (2000-06-01), None
patent: WO 00 63701 (2000-10-01), None
patent: WO 01/020015 (2001-03-01), None
patent: WO 01/45843 (2001-06-01), None
Smith et al. The Analysis of Doxorubicin Resistance in Human Breast Cancer Cells Using Antibody Microarrays; Molecular CAncer Therapeutics, vol. 5, No. 8 (2006) pp. 2115-2120.
Tanaka et al. Drug Response Assay System in a Microchip Using Human Hepatoma Cells; Analytical Sciences, vol. 20 (2004) pp. 411-413.
Sambrook, et al. “Molecular Cloning: A Laboratory Manual,” 3rd Edition, Cold Spring Harbor Laboratory Press, 2001, pp. 1.126-1.134.
Tobery, et al., “A Simple and Efficient Method for the Monitoring of Antigen-Specific T Cell Responses Using Peptide Pool Arrays in a Modified ELISpot Assay,” Journal of Immunological Methods, vol. 254, No. 1-2, Aug. 1, 2001, pp. 59-66.
Lin, et al., “Cholera Toxin-Induced Moducation of Gene Expression: Elucidation via cDNA Microarray for Rational Cell-Based Sensor Design,” Analytica Chimica Acta, vol. 457, No. 1, 2002, pp. 97-108.
The Japanese Biochemical Society, entitled “New Biochemical Experimental Course 1 Protein I-Separation, Purification and Property,” 1990, pp. 399-403.
The Japanese Biochemical Society, entitled “New Biochemical Experimental Course 2 Nucleic-acid II-Structure and Property,” 1991, pp. 197-209.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for high throughput cell-based assays using versatile... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for high throughput cell-based assays using versatile..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for high throughput cell-based assays using versatile... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3979882

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.