Method for high loading of vesicles with biopolymeric substances

Details Method for high loading of vesicles with biopolymeric substances Method for high loading of vesicles with biopolymeric substances

1996-09-09

2000-12-05

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424 943, 424812, 436829, 935 54, 264 41, 264 43, A61K 9127, A61K 9133

Patent

active

061563374

ABSTRACT:
A method for loading liposomes with biopolymeric substances functional in humans involves combining a physiologically compatible solution of the biopolymeric substances with one or more dry, liposome-forming lipids, effecting a lipid-containing fraction, combining the lipid-containing fraction with an organic solvent, effecting an organic solvent fraction, and drying the organic solvent fraction, which effects a dry fraction of liposomes loaded with the biopolymeric substances.

REFERENCES:
patent: 4235871 (1980-11-01), Papahadjopoulos
patent: 4348384 (1982-09-01), Horikoshi
patent: 4370349 (1983-01-01), Evans
patent: 4877561 (1989-10-01), Iga
patent: 5230899 (1993-07-01), Park
patent: 5362442 (1994-11-01), Kent

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