Method for glycosylating hydroxylysine residues

Details Method for glycosylating hydroxylysine residues Method for glycosylating hydroxylysine residues

2008-03-11

2008-03-11

Saidha, Tekchand (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

C435S041000, C435S183000, C435S189000, C435S252300, C435S320100, C536S023200

Reexamination Certificate

active

07341853

ABSTRACT:
This invention relates to a multifunctional enzyme having lysyl hydroxylase and glycosyltransferase activity and to the use of the enzyme in glycosylating hydroxylysine residues. In particular this invention relates to a method for producing glycosyltransferase activity, which comprises that a nucleotide sequence encoding lysyl hydroxylase and glycosyltransferase activity is introduced and expressed in a chosen host and the protein product is recovered from the host cell or from the culture medium.

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