Method for genetically manipulating peptide synthetases

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4351723, 435183, C12P 2102, C12N 900

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active

056521162

ABSTRACT:
Disclosed is a novel method for the in vivo and in vitro synthesis of modified peptides, using either engineered microorganisms capable of expressing peptide synthetases with modified substrate specificity, or peptide synthetases extracted from said microorganisms.

REFERENCES:
Cosmina, P., et. al. (1993) Mol. Microbiol. 8(5), 821-831.
Vosman, B. et. al. (1986) Mol. Gen. Genet. 204, 524-531.
Vollenbroich, D., et al. (1993) FEBS Lett. 325(3), 220-224.
Galli, G., et. al. (1994) Bio Chim. Bio Phys. Acta 1205, 19-28.
Nakano, M.M. et. al. (1991) J. Bacteriol. 173(5), 1770-1778.
Vollenbroich, D., et. al. (1994) J. Bacteriol 176(2), 395-400.
D'Souza, C., et. al. (1993) J. Bacteriol. 175(11), 3502-3510.
Bellini, A.V., et. al. (1988) Gene 69, 325-330.
Stachelhaus, T, et. al. (1995) Science 269, 69-72.
Kleinkauf, H, et. al. (1990) Eur. J. Biochem. 192, 1-15.
Van Sinderen, D., et. al. (1993) Mol. Microbiol. 8(5), 833-841.
Borchert, S., et. al. (1992) FEMS Microbiol. Lett. 92, 175-180.

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