Method for generating oxygen in an excited electronic state and

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128362, A61M 3700

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active

043053904

ABSTRACT:
A system for inactivation of microorganisms and their products (viruses, bacteria, toxins and cells) such as, for example, Herpes simplex viruses by superposition of a component such as, for example, methylene blue (MB) plus light, oxygen and electricity. The system serves to generate the superoxide radical anion (O.sub.2) and consequently hydrogen peroxide (H.sub.2 O.sub.2) and the hydroxyl radical (OH.), both of which enter into the inactivation process, but each has use beyond said system. The disclosed activating components include methylene blue covalently bonded to conconavalin A to enhance its binding to mammalian lymphoblasts and compounds of d.sup.- and f.sup.- transition metals such as cis-platinum diamino dichloride.

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patent: 3591679 (1971-07-01), Voss
patent: 4181128 (1980-01-01), Swartz
patent: 4199419 (1980-04-01), Holroyd et al.

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