Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – Transgenic nonhuman animal
Reexamination Certificate
2007-11-20
2007-11-20
Bertoglio, Valarie (Department: 1632)
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
Transgenic nonhuman animal
C800S008000, C800S003000, C800S024000
Reexamination Certificate
active
09558149
ABSTRACT:
Dominant negative alleles of human mismatch repair genes can be used to generate hypermutable cells and organisms. By introducing these genes into cells and transgenic animals, new cell lines and animal varieties with novel and useful properties can be prepared more efficiently than by relying on the natural rate of mutation.
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Quian,
Kinzler Kenneth W.
Nicolaides Nicholas
Vogelstein Bert
Banner & Witcoff , Ltd.
Bertoglio Valarie
The John Hopkins University
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