Refrigeration – Storage of solidified or liquified gas – With sorbing or mixing
Patent
1998-01-06
2000-06-27
Capossela, Ronald
Refrigeration
Storage of solidified or liquified gas
With sorbing or mixing
62 64, 62 68, 62343, F17C 1100
Patent
active
060792159
ABSTRACT:
The present invention is a system and method for freeze granulation of a medium such as a biopharmeceutical product. The medium is put into a chamber and mixed using a pair of counter rotating agitators. The agitators have angled blades or paddles on them in order to induce motion in the medium parallel to the axis of the agitator shafts. A set of liquid nitrogen and liquid carbon dioxide nozzles are attached to the chamber. The liquid nitrogen nozzles spray a mist of liquid nitrogen into the medium. The liquid carbon dioxide nozzles spray carbon dioxide snow into the chamber. The liquid nitrogen and the carbon dioxide can be sprayed into the chamber at the same time or alternately.
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Capossela Ronald
Integrated Biosystems, Inc.
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