Method for forming 2-D crystals of proteins and macromolecules

Details Method for forming 2-D crystals of proteins and macromolecules Method for forming 2-D crystals of proteins and macromolecules

1985-12-23

1987-05-26

Schain, Howard E.

Stock material or miscellaneous articles

Self-sustaining carbon mass or layer with impregnant or...

427 2, 428420, 4284782, 424 85, 530344, 530387, 530389, 530390, 530391, 530396, 530404, 530408, 530412, 530414, 530415, 530422, 530423, 530424, 530427, B32B 900, C07K 300

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046685847

ABSTRACT:
A method is provided for forming ordered macromolecular protein arrays by avoiding a binding pathway that leads to densely packed, disordered states during protein crystal growth, by a diffusion limited process or by allowing controlled growth to occur by removal of the initial supported protein layer to a different environment.

REFERENCES:
patent: 4172827 (1979-10-01), Giaever
patent: 4489133 (1984-12-01), Kornberg
E. E. Uzgiris & R. D. Kornberg, "Two-Dimensional Crystallization Technique for Imaging Macromolecules, with Application to Antigen-Antibody-Complement Complexes", Nature, vol. 301, Jan. 13, 1983, pp. 125-129.

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