Method for fluorodecarboxylation

Details Method for fluorodecarboxylation Method for fluorodecarboxylation

1994-11-16

1997-07-22

Kelly, Cynthia Harris

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568684, 568685, 568655, 570142, 570218, 570261, C07C 4100, C07C 1908, C07C 17361, C07C 1700

Patent

active

RE0355682

ABSTRACT:
The present invention is directed to a method for replacing a carboxylic acid group with a fluorine [group] in a halogenated aliphatic carboxylic acid compound having the formula, R-COOH, to prepare a fluorinated product having the formula, R-F, wherein R is a halogenated aliphatic group including straight- and branched-chain aliphatic groups selected from the group consisting of halogenated aliphatic and halogenated alkoxy-substituted [halogenated] aliphatic groups, wherein the method comprises the step of (a) reacting the halogenated aliphatic carboxylic acid compound with bromine trifluoride, and (b) recovering the fluorinated product.

REFERENCES:
patent: 3683092 (1972-08-01), Regan et al.
patent: 4469898 (1984-09-01), Coon et al.
patent: 4847427 (1989-07-01), Nappa
patent: 4874901 (1989-10-01), Halpern et al.
patent: 4874902 (1989-10-01), Huang et al.
Chem tech, May 1989, pp. 304, 308, Halpern.
J. Org. Chem, vol. 48, (1983) pp. 4158-4159, Patrick et al.
Can. J. of Chem., vol. 64, (1986) pp. 138-141, Patrick et al., "Replacement of the Carboxylic Acid Function with fluoride".

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