Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Patent
1991-12-06
1992-11-03
Therkorn, Ernest G.
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
2101982, 21032189, 21050023, 210637, 210638, 210656, 210659, B01D 1508
Patent
active
051606259
ABSTRACT:
An apparatus for flow field flow (FFF) fractionation comprises: a porous hollow fiber (1) which extends longitudinally between end-fittings (2, 3) of a tube (4), one end of said fiber (1) being connected to a first pump (5) for pumping a first carrier liquid into said fiber (1) via a valve (9) for introducing a liquid sample to be fractionated, the other end of said fiber (1) being connected to a container for a second carrier liquid via a flow-through detector (11), for detecting fractions of said sample; a second pump (12) which is connected to the interspace between the tube (4) and the fiber (1) to pump out carrier fluid through the porous fiber wall; and a control unit (6) which is adapted to control said first pump (5) to have a flower flow rate than said second pump (12) during injection and relaxation of the sample, and a higher flow rate than said second pump (12) to elute the sample; and a method for FFF fractionation in a hollow fiber utilizing the steps of sample application, relaxation, flow restoration, and elution whereby the radial flow out of the fiber is controlled by a separate pump.
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Carlshaf Alf
Jonsson Jan A.
Pharmacia LKB Biotechnology AB
Philpitt Fred
Therkorn Ernest G.
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