Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Patent
1982-09-24
1984-06-19
Shapiro, Lionel M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
435253, 435881, C12P 1324, C12N 120, C12R 143
Patent
active
044553722
ABSTRACT:
A method for the fermentative production of L-proline which comprises cultivating a L-proline-producing mutant of a microorganism belonging to the genus Serratia in a broth to produce and accumulate L-proline therein and collecting accumulated L-proline. The mutant is preferably that of Serratia marcescens which is deficient in L-proline oxidase and is resistant to proline analong under a high osmotic pressure.
REFERENCES:
patent: 4224409 (1980-09-01), Nakamori et al.
Applied and Environmental Microbiology, May 1976, vol. 31, No. 5, pp. 738-742.
Chibata Ichiro
Kisumi Masahiko
Sugiura Masaki
Takagi Tsutomu
Bierman Jordan B.
Bierman Linda
Shapiro Lionel M.
Tanabe Seiyaku Co. Ltd.
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