Chemistry: analytical and immunological testing – Metal or metal containing – Present in biological fluids
Patent
1993-06-03
1995-04-18
Warden, Jill A.
Chemistry: analytical and immunological testing
Metal or metal containing
Present in biological fluids
436 73, 436177, 436178, G01N 3000, G01N 3350
Patent
active
054078318
ABSTRACT:
A simple and sensitive method for extracting an inorganic element, including toxic metals such as lead or antimony or non-metallic elements such as arsenic, selenium or tellurium from animal blood, including human blood, is provided by the present invention. The sample of blood or portion of blood, such as red cells, is first mixed with an neutral salt solution. The mixture of cells and buffer is then exposed to a chelating resin which removes the inorganic element, such as lead, from solution. Thereafter, the resin is packed in a column and the element, such as lead, is eluted. The amount of eluted element, such as lead, is measured by conventional methods, such as atomic absorption spectrophotometry.
REFERENCES:
patent: 4028130 (1977-06-01), Webster et al.
patent: 4403039 (1983-09-01), Ban et al.
patent: 4832847 (1989-05-01), Fujii et al.
patent: 5039618 (1991-08-01), Stone
patent: 5055402 (1991-10-01), Greene et al.
patent: 5094944 (1992-03-01), Hayes
patent: 5149656 (1992-09-01), Bitton et al.
patent: 5193936 (1993-03-01), Pal et al.
Abstract, "Cadmium Uptake by Plants and its Correlation With Sewage Sludge CD Extractability," by Dr. Jung Jing, Feb. 1990.
"Contribution of Social and Developmental Factors to Lead Exposure During the First Year of Life," Pediatrics, by Kim N. Dietrich et al., vol. 75, No. 6, Jun. 1985, pp. 1114-1119.
"Assessing the Contribution From Lead in Mining Wastes to Blood Lead," Regulatory Toxicology and Pharmacology, by Martha J. Steele et al., 1990, pp. 158-190.
"Bioavailability of Arsenic and Lead in Soils from the Butte, Montana, Mining District," Environ. Sci. Technol., by Andy Davis et al., vol. 26, No. 3, 1992, pp. 461-468.
"Lead Bioavailability: Dissolution Kinetics Under Simulated Gastric Conditions," Environ. Sci. Technol., by Michael V. Ruby et al., vol. 26, No. 6, pp. 1242-1248.
"Relative Bioavailability of Lead From Mining Waste Soil in Rats," Fundamental and Applied Toxicology, by G. B. Freeman et al., vol. 19, 1992, pp. 388-398.
"Estimation of Isotopically Exchangeable Cadmium and Zinc in Soils," by R. Fujii and R. B. Corey, Soil Sci. Soc. Am. J., vol. 50, 1986.
"A Method for Controlling the Activities of Free Metal Hydrogen, and Phosphate Ions in Hydroponic Solutions Using Ion Exchange and Chelating Resins," by Checkai et al., Plant and Soil 99, 321-334, 1987.
"Chelating Resin Method for Estimation of Sludge-Cadmium Bioavailability," by J. Jing et al., Commun. Soil Sci. Plant Anal., 22(19&20), 2029-2035 (1991).
"A Chelating-Resin Method for Characterizing Soluble Metal Complexes," by L. L. Hendrickson et al., Soil Sci. Soc. Am. J., 47:467-474, 1983.
"Use of Chelating Resins in Metal Adsorption tudies," by M. A. Turner et al., Soil Sci. Soc. Am. J., 48:763-769, 1984.
"Heavy Metals in the Environment, Effects of Sewage Sludge Cadmium Concentration on Chemical Extractability and Plant Uptake," by Jung Jing et al., J. Environ. Qual., 21:73-81, 1992.
Abstract entitled "bioavailability of Cadmium in Municipal Sewage Sludge," vol. 51, No. 10, Apr. 1991, Dissertation Abstracts International.
Thesis entitled "Bioavailability of Cadmium in Municipal Sewage Sludge," by Jung Jing, The Ohio State University, 1990.
The Ohio State University Research Foundation
Warden Jill A.
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