Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution...
Reexamination Certificate
2003-10-21
2008-03-25
Tate, Christopher R (Department: 1655)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
C424S400000
Reexamination Certificate
active
07348032
ABSTRACT:
A method for extracting antineoplastic component fromBupleurum scorzonerifoliumapplicable in treating cell proliferative disorder is proposed. The antineoplastic components ofBupleurum scorzonerifoliuminclude at least a Y-butyolactone centred heterocyclic compound with a Z configuration or E configuration at its carbon 2(5) position, and molecules, such as Chaihulactone, Isochaihulactone, Chaihulactone analogues or derivatives containing in the heterocyclic compound. From results of cell and molecular biological studies, in vivo animal test, and histological study, it is found that antineoplastic components extracted fromBupleurum scorzonerifoliumare effective in suppressing a variety of cancer cell growths, inhibiting telomerase activity, as well as effective in killing with high specificity Taxol-resistant tumor cells at later stage of chemical therapy, making the components a new choice for anti-cancer agent, anti-HIV agent, or synergistic agent.
Harn Horng-Jyh
Lin Shinn-Zong
Buddhist Tzu Chi General Hospital
Corless Peter F.
Edwards Angell Palmer & & Dodge LLP
Kim Dwight D.
Tate Christopher R
LandOfFree
Method for extracting antineoplastic components from... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for extracting antineoplastic components from..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for extracting antineoplastic components from... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3980985