Surgery – Blood drawn and replaced or treated and returned to body – Constituent removed from blood and remainder returned to body
Patent
1983-06-30
1984-08-07
Lesmes, George F.
Surgery
Blood drawn and replaced or treated and returned to body
Constituent removed from blood and remainder returned to body
128 1R, 128395, 128DIG3, 422 44, 604 20, 604 28, A61M 103
Patent
active
044641664
ABSTRACT:
A method and system are disclosed for externally treating human blood, with the objective of reducing the functioning lymphocyte population in the blood system of a human subject. According to the method, blood is withdrawn from the subject and passed throught an ultraviolet radiation field in the presence of from about 1 nanogram to 100 micrograms per ml of blood, of a dissolved photoactive agent capable of forming photo-adducts with lymphocytic-DNA, mobile cortisone receptors or antigen sites to thereby effect covalent bonding between the photoactive agent and the same, thereby inhibiting the metabolic processes of the lymphocytes or complexing them; and thereupon returning the irradiated blood to the subject. The withdrawn blood may be formed into an extracorporeal stream and flowed through a treatment station whereat the irradiation is effected, as for example by exposure to UV radiation; and such flow process may be conducted on a continuous basis. If desired, at least portions of the treated blood may then be separated, as for example by a continuous centrifuge, before returning the remaining diverted blood to the subject.
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patent: 4321918 (1982-03-01), Clark
patent: 4381004 (1983-04-01), Babb
Bourke Eleanor F.
Bourke, Jr. Frederic A.
Edelson Richard L.
Lesmes George F.
Swisher Nancy A. B.
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