Optics: measuring and testing – By shade or color – With color transmitting filter
Reexamination Certificate
2005-11-01
2005-11-01
Toatley, Jr., Gregory J. (Department: 2877)
Optics: measuring and testing
By shade or color
With color transmitting filter
C250S459100, C359S326000
Reexamination Certificate
active
06961124
ABSTRACT:
A method for examining a specimen (27) that exhibits at least two optical transition lines and is optically excitable at least with light of a first and light of a second wavelength is characterized by the step of illuminating the specimen (27) with illuminating light (15) that generates at least a multiple of the first wavelength and a multiple of the second wavelength; and by the step of detecting the detected light (29) proceeding from the specimen (27).Also disclosed is a scanning microscope system (1) having at least one light source (3) that emits illuminating light (15) for illumination of a specimen (27), the specimen (27) exhibiting at least two optical transition lines and being optically excitable at least with light of a first and light of a second wavelength, having at least one detector (41, 43, 65, 77, 79) for detection of the detected light (29) proceeding from the specimen (27) and an objective (25) for focusing the illuminating light (15) onto a subregion of the specimen (27). The scanning microscope system is characterized in that the illuminating light (15) generates at least a multiple of the first wavelength and a multiple of the second wavelength.
REFERENCES:
patent: 5034613 (1991-07-01), Denk et al.
patent: 5304810 (1994-04-01), Amos
patent: 5796477 (1998-08-01), Teich et al.
patent: 5886784 (1999-03-01), Engelhardt
patent: 5891738 (1999-04-01), Soini et al.
patent: 6020591 (2000-02-01), Harter et al.
patent: 6154310 (2000-11-01), Galvanauskas et al.
patent: 6159686 (2000-12-01), Kardos et al.
patent: 6166385 (2000-12-01), Webb et al.
patent: 6169289 (2001-01-01), White et al.
patent: 6344653 (2002-02-01), Webb et al.
patent: 6405070 (2002-06-01), Banerjee
patent: 6528802 (2003-03-01), Koenig et al.
patent: 6667830 (2003-12-01), Iketaki et al.
patent: 195 20 563 (1996-12-01), None
patent: 196 21 512 (1997-12-01), None
patent: 4414940 (1998-07-01), None
patent: 19902625 (1999-09-01), None
patent: 0495930 (1999-04-01), None
Centonze, Victoria E. et al. , “Multiphoton Excitation provides optical sections from deeper within scattering specimens than confocal imaging” Biophys J. Oct. 1998., p. 2015-2024, vol. 75, No. 4, http://www.biophysj.org/cgi/content/full/75/4/2015, Nov. 24, 2003.
Shear, Jason B., “Multiphoton Excited Fluorescence in Bioanylytical Chemistry” Analyical Chemistry News and Features, Sep. 1, 1999; pp598A-605A.
Engelhardt Johann
Hoffmann Juergen
Geisel Kara E.
Leica Microsystems Heidelberg GmbH
Simpson & Simpson PLLC
Toatley , Jr. Gregory J.
LandOfFree
Method for examining a specimen, and scanning microscope system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for examining a specimen, and scanning microscope system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for examining a specimen, and scanning microscope system will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3474434