Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1989-11-28
1992-06-23
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 79, 435965, G01N 3353, G01N 33542, G01N 33577
Patent
active
051242494
ABSTRACT:
Venom immunotherapy is a highly effective treatment for bee sting sensitive individuals. Treated individuals and those naturally exposed to repeated bee stings, such as beekeepers have been shown to develop anti bee venom anti-idiotypic antibodies. These antibodies can be isolated, monoclonal anti-bee venom antibodies can be generated and used in a diagnostic kit to evaluate whether or not an affected individual has developed effective immunity and to evaluate an individual's risk of sensitivity.
REFERENCES:
patent: 4536479 (1985-08-01), Vander-Mallie
Saxon et al., J. Clin. Invest. 73:342-348, 1984.
Bose et al., J. Immunol. 135:2474-2478, 1984.
Towbin et al., J. Immunol. Methods 72:313-340, 1984.
Sigma Immunochemicals, 1989 catalog, St. Louis, Mo., Item A5026.
Sevier et al., Clin. Chem. 27:1797-1806, 1981.
Maggio, E. T., Ed., Enzyme Immunoassay, CRC Press, Boca Raton, Fla., 1980, pp. 167-179.
Day James H.
Khan Rashid H.
Szewczuk Myron R.
Kepplinger Esther L.
Wortman Donna C.
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