Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-12-28
2009-10-20
Cook, Lisa V (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007100, C435S041000, C436S501000, C436S543000, C530S300000, C530S350000
Reexamination Certificate
active
07604954
ABSTRACT:
Methods for (1) evaluating feline kidney function by determining ghrelin level in feline tissue or biofluid and correlating the ghrelin level directly to kidney function and (2) diagnosing kidney disease in a feline comprises determining an observed ghrelin level in a tissue or biofluid of the feline and comparing the observed ghrelin level to a reference ghrelin level indicative of normal kidney function, wherein an observed level lower than the reference level is indicative of kidney disease or susceptibility thereto.
REFERENCES:
patent: WO 2005/094200 (2005-10-01), None
Ida et al. (Domestic Animal Endocrinology, vol. 32, pp. 93-105, 2007).
Yoshimoto et al. (Journal of American Society of Nephrology, vol. 13, No. 11, pp. 2748-2752, 2002).
Guebre-Egziabher et al. (Journal of Renal Nutrition, vol. 15, No. 1, Jan. 2005, pp. 116-120).
Gale, Susan M., et al., “Energy Homeostasis, Obesity and Eating Disorders: Recent Advances in Endocrinology”, The Journal of Nutrition, 134:295-298; 2004.
Guebre-Egziabher, Fitsum, et al., “Leptin, Adiponectin, and Ghrelin Dysregulation in Chronic Kidney Disease” Journal of Renal Nutrition, 15:116-120; 2005.
AkihiroYoshimoto et al. ,“Plasma Ghrelin and Desacyl Ghrelin Concentrations in Renal Failure”,Journal of the American Society of Nephrology, Williams and Wilkins, Baltimore, MD, vol. 13, No. 11, Nov. 2002, pp. 2748-2752. XP002390260.
Friesen Kim Gene
Yamka Ryan Michael
Cook Lisa V
Hill's Pet Nutrition, Inc.
McGarrah Shannon
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