Method for evaluating immunotoxicity of test substance

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S026000, C435S029000, C435S032000

Reexamination Certificate

active

07148007

ABSTRACT:
The present invention discloses a method of evaluating the immunotoxicity of a hydrophobic test substance, comprising (1) culturing immunocompetent cells in a culture system containing a hydrophobic test substance and a surfactant, (2) obtaining a survival rate of the immunocompetent cells after the culturing (1), and (3) evaluating the immunotoxicity of the hydrophobic test substance from the survival rate obtained in (2).

REFERENCES:
patent: 5801193 (1998-09-01), Ojo-Amaize et al.
patent: 6265180 (2001-07-01), Zuelli et al.
patent: 6587845 (2003-07-01), Braunheim
patent: 6723527 (2004-04-01), Pettit et al.
patent: 6969729 (2005-11-01), Jensen et al.
patent: 2003/0040025 (2003-02-01), Ishihara et al.
patent: 0953632 (1999-02-01), None
Kacani et al, Folia Biologica (Praha), 42, 11-16, 1996.
C. W. Johnson, et al. “Sensitivity of the SRBC PFC Assay Versus Elisa for Detection of Immunosuppression by TCDD and TCDD-Like Congeners” Toxicology, 2000, pp. 1-11.
Beths A. Vorderstrasse, et al. “2,3,7,8-Tetrachlorodibenzo-P-Dioxin Affects the Number and Function of Murine Splenic Dendritic Cells and Their Expression of Accessory Molecules” Toxicology and Applied Pharmacology, 2001, pp. 117-125.
Satoshi Itoh, et al. “Relationship Between Toxicity and Electronic Strucutres of Dioxins: DFT and Neural-Network Approaches” AlChE Symposium Series vol. 97, 2001, pp. 180-182.
U.S. Appl. No. 11/174,660, filed Jul. 6, 2005, Itoh.
Toshihiro Fujii, et al., “Quantitative Risk (Toxicity) Evaluation System for Dioxin, Session of Research Report on Research and Development for Applying Advanced Computational Science and Technology-Progressive Third Science”, Japan Science and Technology Agency, H10 (1998) Short Term Type, Dec. 31, 2000, pp. 96-97.
Shinichi Kikuchi, et al., “Discovery of Rules and Improvement of Generalization Power using SFNN and Destructive Structural Learning Algorithm”, Technical Research Report of the Institute of Electronics, Information and Communication Engineers, vol. 98, No. 219, Jul. 27, 1998, pp. 31-38, (with English Abstract).
Ikuo Moriguchi, “Development of Quantitative Structure-Activity Relationships and Computer-Aided Drug Design”, Pharmaceutical Society of Japan, vol. 114, No. 3, Mar. 25, 1994, pp. 135-146.

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