Method for enhancing transport of gases to tissues

Details Method for enhancing transport of gases to tissues Method for enhancing transport of gases to tissues

1996-11-26

1999-02-09

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Halogenated hydrocarbon doai

514746, 514749, A61K 3102, A61K 31035, A61K 3103

Patent

active

058695389

ABSTRACT:
Disclosed are methods of using stabilized microbubbles, such as those formulated from slowly permeating gas, to deliver or remove from tissue at least one gas selected from a respiratory gas, anesthetic gas, inert gas, or toxic gas. The methods comprise introducing, into the blood circulation of an individual to be treated, a therapeutically effective amount of the stabilized microbubbles. The methods are based on using the inherent physical properties of the blood circulation, of the microbubbles, and of the gases. The methods are especially useful for enhancing transport of oxygen in applications or conditions such as blood loss, anemia, organ perfusion, coronary Angioplasty, venous to arterial shunting of blood, oxygenation of ischemic tissues resulting from vascular obstructions, and oxygenation of solid tumor tissues in anticancer therapy.

REFERENCES:
patent: 5213570 (1993-05-01), VanDeripe
patent: 5393524 (1995-02-01), Quay
patent: 5409688 (1995-04-01), Quay

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