Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-05-22
1992-11-17
Ore, Dale R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514396, 514397, 514651, 514938, 514946, 514947, A61K 3140, A61K 3144
Patent
active
051644061
ABSTRACT:
The present invention provides for a composition containing a pharmacologically active agent and a selected imidazole or an imidazole derivative, such composition exhibiting enhanced penetration of the pharmacologically active agent component when a composition containing the aforementioned components is applied to skin.
A method of enhancing dermal penetration of compositions containing a pharmacologically active agent is also provided.
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patent: 4732892 (1988-03-01), Sarpotdar et al.
patent: 4879275 (1989-11-01), Minaskanian
patent: 4908389 (1990-03-01), Mahjour et al.
Iwata et al., "Adriamycin Ointment with Addition of Napholine Nitrate . . . ", Yakuzaigaku, 48, (1), (1988), pp. 64-69, Chem. Abs., Sep. 5, 1988, vol. 109, No. 10, 79612b.
Helman Michael D.
Lukacsko Alison B.
Re Thomas A.
Zusi F. Christopher
Bristol-Myers Squibb Co.
Nolan Sandra M.
Ore Dale R.
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