Method for enhancing the lowering of plasma-cholesterol levels

Details Method for enhancing the lowering of plasma-cholesterol levels Method for enhancing the lowering of plasma-cholesterol levels

1993-02-01

1994-12-27

Phelan, D. Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

514460, A61K 924

Patent

active

053763831

ABSTRACT:
The instant invention is directed to a method for enhancing the lowering of plasma cholesterol level in a subject in need thereof which comprises the time-controlled administration of a nontoxic therapeutically effective amount of an HMG-CoA reductase inhibitor to said subject which surprisingly affords an equivalent or improved reduction of plasma cholesterol levels while significantly reducing the amount of HMG-CoA reductase inhibitor circulating in the bloodstream of the subject as compared to the same parameters when the oral administration of a conventional rapid release dosage form is utilized.

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