Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Para-n-benzene - sulfoxy-n containing doai – and said benzene...
Patent
1990-02-14
1991-04-16
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Para-n-benzene - sulfoxy-n containing doai, and said benzene...
514275, A61K 3163, A61K 31505
Patent
active
050082558
ABSTRACT:
A method of preparing aqueous pharmaceutical compositions containing a synergistic combination of trimethoprim and sodium sulfacetamide is described. The method results in a significant improvement in the aqueous solubility of trimethoprim due to a favorable interaction between the trimethoprim and sodium sulfacetamide which is dependent on a mildly acidic pH.
REFERENCES:
patent: 3985873 (1976-10-01), Alvan et al.
Ali Yusuf
Edwards John G.
Han Wesley W.
Alcon Laboratories Inc.
Arno James A.
Brown Gregg C.
Goldberg Jerome D.
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