Method for enhancing protective cellular responses to...

Details Method for enhancing protective cellular responses to... Method for enhancing protective cellular responses to...

2002-09-27

2008-09-16

Padmanabhan, Sreeni (Department: 1617)

Drug, bio-affecting and body treating compositions

Topical sun or radiation screening, or tanning preparations

C424S401000, C514S351000, C514S353000, C514S356000

Reexamination Certificate

active

07425319

ABSTRACT:
The present invention is directed to methods of using pro-NAD agents capable of enhancing the dermal and epidermal skin cell NAD content. These pro-NAD agents may be administered topically, orally, or parenterally to enhance DNA repair and other protective responses to DNA damage. The invention further relates to pharmaceutical compositions comprising pro-NAD agents that effectively elevate intracellular NAD content. Finally, the invention relates to the method of using the pro-NAD agents to treat disorders such as sunburn and other skin deterioration that results from DNA damage in skin cells.

REFERENCES:
patent: 4683310 (1987-07-01), Dalton et al.
patent: 4775763 (1988-10-01), Dalton et al.
patent: 4847260 (1989-07-01), Abe et al.
patent: 5939082 (1999-08-01), Oblong et al.

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