Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1986-10-07
1988-03-15
Marantz, Sidney
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
128653, 128654, 436173, 436526, 436806, A61K 4900, A61B 600, A61B 505
Patent
active
047312394
ABSTRACT:
An improvement in NMR imaging techniques is disclosed, whereby the image is "shadowed" to intensify and contrast the image generated by the NMR sensitive nuclei, as a consequence of the introduction to the examined locus, e.g., human tissue of ferromagnetic, diamagnetic or paramagnetic particles. The intensified and clarified image is itself diagnostically valuable, in accordance with art recognized methods but also provides an improved information base for establishing and controlling treatment modes, especially in determining spatial density and distribution of particles by comparing standard and enhanced images. According to a preferred embodiment, metabolizable particles are employed, whereby the change and rate of change with metabolic time can be imaged, compared, and correlated with various metabolic diseases or malignant states.
REFERENCES:
patent: 3474777 (1969-10-01), Figge et al.
patent: 3592185 (1971-07-01), Frei
patent: 3681245 (1972-08-01), Lee
patent: 3700555 (1972-10-01), Widmark et al.
patent: 3832457 (1974-08-01), Sugimoto et al.
patent: 3917538 (1975-11-01), Rosenweig
patent: 3922687 (1975-11-01), Trimble et al.
patent: 4001288 (1977-01-01), Gable et al.
patent: 4018886 (1977-04-01), Giaever
patent: 4047814 (1977-09-01), Westcott
patent: 4101435 (1978-07-01), Hasegawa
patent: 4106488 (1978-08-01), Gordon
patent: 4136683 (1979-01-01), Gordon
patent: 4187170 (1980-02-01), Westcoh et al.
patent: 4255492 (1981-03-01), Audran et al.
patent: 4269826 (1981-05-01), Zimmermann et al.
patent: 4323056 (1982-04-01), Borrelli et al.
patent: 4335094 (1982-06-01), Mosbach
patent: 4345588 (1982-08-01), Widder et al.
patent: 4359453 (1982-11-01), Gordon
patent: 4360441 (1982-11-01), Borrelli et al.
patent: 4364377 (1982-12-01), Smith
patent: 4392040 (1983-07-01), Rand et al.
patent: 4452773 (1984-06-01), Molday
patent: 4454106 (1984-06-01), Gansow et al.
patent: 4508625 (1985-04-01), Graham
patent: 4615879 (1986-10-01), Runge et al.
patent: 4647447 (1987-03-01), Gries et al.
Horrocks, Jr. et al., "Lanthanide Porphyrin Complexes", Journ. of the Am. Chem. Soc., 198:231, 11/10/76.
Fabs letters, vol. 168, No. 1, Mar. 1984, pp. 70-74.
Kaiser, Robert, IEEE Transactions on Magnetics, vol. 6, No. 3, Sep. 1970, pp. 694-698.
Runge et al., Int. J. Nucl. Med. Biol., vol. 12, No. 1, pp. 37-42, 1985.
New Scientist, 15 Mar. 1979, pp. 874-877.
Journal of Pharmaceutical Sciences, vol. 68, No. 1, Jan. 79, pp. 79-81, Widder et al.
Chem. Abstract, vol. 99, 1983, p. 232-CA:49837.
Newbower, Ronald, IEEE Transactions on Magnetics, vol. Mag. 9, No. 3, Sep. 1973, pp. 447-450.
Marantz Sidney
Wieder Stephen C.
LandOfFree
Method for enhancing NMR imaging; and diagnostic use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for enhancing NMR imaging; and diagnostic use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for enhancing NMR imaging; and diagnostic use will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1925699