Radiant energy – Ionic separation or analysis – Methods
Reexamination Certificate
2007-08-21
2009-08-04
Wells, Nikita (Department: 2881)
Radiant energy
Ionic separation or analysis
Methods
C250S292000, C250S281000, C250S252100
Reexamination Certificate
active
07569813
ABSTRACT:
A method of operating an ion trap spectrometer system having an ion trap is provided. The method comprises a) providing a group of ions for analysis, wherein the group of ions includes a first analyte; b) providing a filtered first analyte having a first mass-to-charge ratio by filtering out ions other than the first analyte; c) storing the filtered first analyte in the ion trap; d) storing a first set of calibrant ions in the ion trap with the filtered first analyte, wherein the first set of calibrant ions has at least one calibrant ion and each calibrant ion in the first set of calibrant ions has a known mass-to-charge ratio; e) transmitting the filtered first analyte and the first set of calibrant ions from the ion trap for detection; f) detecting the filtered first analyte to generate a first analyte mass signal peak representing the filtered first analyte, and detecting each calibrant ion in the first set of calibrant ions to generate an associated calibrant mass signal peak for each calibrant ion in the first set of calibrant ions; and, g) calibrating a first mass signal derived from the first analyte mass signal peak by comparing the known mass-to-charge ratio and the associated calibrant mass signal peak for each calibrant ion in the first set of calibrant ions.
REFERENCES:
patent: 5572025 (1996-11-01), Cotter et al.
patent: 6504148 (2003-01-01), Hager
patent: 7227130 (2007-06-01), Hager et al.
patent: 7365319 (2008-04-01), Hager et al.
patent: 2003/0138823 (2003-07-01), Brock et al.
patent: 2004/0188605 (2004-09-01), Tang et al.
patent: 2005/0023454 (2005-02-01), Bateman et al.
patent: 2006/0108520 (2006-05-01), Park et al.
patent: 2007/0164231 (2007-07-01), Truche et al.
Jon D. Williams et al., “Improved accuracy of mass measurement with a quadrupole ion-trap mass spectrometer”: Rapid Communications in Mass Spectrometry, vol. 6, pp. 524-527, 1992, whole document.
International Search Report and Written Opinion, PCT/CA2007/001459, date of mailing May 15, 2008.
J. Mitchell Wells, Wolfgang R. Plass, R. Graham Cooks; “Control of Chemical Mass Shifts in the Quadrupole Ion Trap through Selection of Resonance Ejection Working Point and rf Scan Direction”; Analytical Chemistry, vol. 72, No. 13, Jul. 1, 2000; pp. 2677-2683.
Applied Biosystems LLC
Bereskin & Parr LLP / S.E.N.C.R.L., s.r.l.
MDS Analytical Technologies, a business unit of MDS Inc.
Wells Nikita
LandOfFree
Method for enhancing mass assignment accuracy does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for enhancing mass assignment accuracy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for enhancing mass assignment accuracy will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4059308