Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1990-08-13
1992-01-07
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
424 2, 436173, 436806, 514558, 514563, 514974, A61K 3120, A61K 31195, G01N 3100, G01N 2400
Patent
active
050789864
ABSTRACT:
Nuclear magnetic resonance (NMR) imaging of body organs and tissues is enhanced by administering to a living animal body a substantially nontoxic paramagnetic image altering agent comprised of a composition containing a chelate of a paramagnetic element, such as manganese, gadolinium or iron, carried by a liposome. The chelate is carried by or within the external surface of the liposome in such a manner that after arrival at or delivery to the desired organ or tissue site, the paramagnetic image altering agent is released in a diagnostically useful fashion.
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Bosworth Mark E.
Hopkins Ronald M.
Hollinden Gary E.
Hollrah Glennon H.
Mallinckrodt Medical Inc.
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