Method for enhancing healing of corneal endothelial wounds

Details Method for enhancing healing of corneal endothelial wounds Method for enhancing healing of corneal endothelial wounds

1989-04-13

1991-09-24

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514448, 514563, A61K 3140, A61K 3138, A61K 31195

Patent

active

050514431

ABSTRACT:
The composition and method of using a non-steroidal antiinflammatory compound, such as indomethacin and/or a growth factor that causes a change in cell function when bound to specific cell surface receptor, such as epidermal growth factor (EGF), to enhance healing and restore function of the corneal endothelium. The compositions can be administered alone, in combination, or in sequence, before or after injury, for example, in an irrigation solution or in combination with a nutritive solution for storage of cornea prior to transplant.

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