Method for enhancing growth of mammary parenchyma

Details Method for enhancing growth of mammary parenchyma Method for enhancing growth of mammary parenchyma

1990-03-14

1992-07-14

Moezie, F. T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, 514 2, A61K 3724, A61K 3736

Patent

active

051303000

ABSTRACT:
The growth of milk-producing mammary parenchyma in a mammal can be significantly enhanced by administering to the mammal by intramammary infusion a substance having a mitogenic effect on mammary epithelial cells in said mammal. Good growth enhancement can be achieved using very small quantities of such substances, and in relatively short periods of time.

REFERENCES:
patent: 4742003 (1988-05-01), Derynck et al.
patent: 4816561 (1989-03-01), Todaro
patent: 4816561 (1989-03-01), Todaro
patent: 5059586 (1991-10-01), Collier
".alpha.-Transforming Growth Factor Secreted by Untransformed Bovine Pituitary Cells in Culture" Samsoondar et al., J. Biological Chemistry 261:14408-14413 (1986).
Korbin, M. S. et al. (1987) Endocrinology 121: 1412-1416 ".alpha.-Transforming Growth Factor in Bovine Anterior Pituitary Gland: Secretion by Dispersed Cells and Immunohistochemical Localization".
Eisa, JP0014799, published Jan. 1988, Abstract in English.

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