Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical
Patent
1997-07-23
2000-05-02
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Food or edible as carrier for pharmaceutical
424456, A61K 948
Patent
active
060569719
ABSTRACT:
A method for enhancing the dissolution properties of relatively insoluble dietary supplements is provided in accordance with the invention. The method includes the steps of providing at least one relatively water insoluble dietary supplement, solubilizing the dietary supplement with a solubilizer, and incorporating an edible polyhydric alcohol into the solubilized dietary supplement to provide a liquid dietary supplement composition that will dissolve spontaneously in the gastrointestinal tract with the minimum agitation which normally occurs there due to peristaltic action. The liquid dietary supplement composition can be readily supplied by incorporation in a gelatin capsule and a gelatin capsule having a liquid dietary supplement incorporated therein is also provided in accordance with the invention. The gelatin capsule dissolves readily in the digestive tract and the dietary supplement has enhanced bioavailability in comparison to prior art gelatin capsules.
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Aufrichtig Peter D.
Biosytes USA, Inc.
Page Thurman K.
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