Method for enhanced electrotransport agent delivery

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – C-o-group doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514725, 514783, 128783, A61K 31045, A61K 3107, A61K 4700, A61B 1000

Patent

active

058614397

ABSTRACT:
An electrotransport composition comprises at least one C.sub.2 -C.sub.4 lower alcohol, unsaturated derivatives thereof, or mixtures thereof, and at least one C.sub.8 -C.sub.14 higher alcohol, unsaturated derivatives thereof, or mixtures thereof. An electrotransport device and a method of increasing transdermal electrotransport flux utilize the composition of the invention for delivering pharmaceutically-acceptable agents across a body surface such as skin.

REFERENCES:
patent: 4250878 (1981-02-01), Jacobsen et al.
patent: 4593048 (1986-06-01), Sato
patent: 4615699 (1986-10-01), Gale et al.
patent: 4645502 (1987-02-01), Gale et al.
patent: 4692328 (1987-09-01), Kitchell et al.
patent: 4722726 (1988-02-01), Sanderson et al.
patent: 4752612 (1988-06-01), Saito et al.
patent: 4927408 (1990-05-01), Haak et al.
patent: 5002956 (1991-03-01), Thiel
patent: 5023085 (1991-06-01), Francoeur et al.
patent: 5080646 (1992-01-01), Theeuwes et al.
patent: 5125894 (1992-06-01), Phipps et al.
patent: 5147296 (1992-09-01), Theeuwes et al.
patent: 5162042 (1992-11-01), Gyory et al.
patent: 5169382 (1992-12-01), Theeuwes et al.
patent: 5169383 (1992-12-01), Gyory et al.
patent: 5221254 (1993-06-01), Phipps
patent: 5232438 (1993-08-01), Theeuwes et al.
patent: 5234992 (1993-08-01), Gyory et al.
patent: 5240495 (1993-08-01), Gyory et al.
patent: 5298017 (1994-03-01), Theeuwes et al.
patent: 5312439 (1994-05-01), Loeb
patent: 5322502 (1994-06-01), Theeuwes et al.
patent: 5344394 (1994-09-01), Gyory et al.
patent: 5356632 (1994-10-01), Gross et al.
patent: 5380271 (1995-01-01), Gyory
patent: 5403275 (1995-04-01), Phipps
Srinivasan, V., et al., Journal of Pharmaceutical Sciences, vol. 79, No. 7, Jul. 1990, pp. 588-591, Iontophoresis of Polypeptides: Effect of Ethanol Pretreatment of Human Skin.
Rolf, David, Pharmaceutical Technology, Sep. 1988, pp. 130-138, "Chemical and Physical Methods of Enhancing Transdermal Drug Delivery".
Kontturi, et al., Pharmaceutical Research, vol. 10, No. 3, 1993, pp. 381-385, "Electrochemical Characterization of Human Skin by Impedance spectroscopy: The Effect of Penetration Enhancers".
Cullander, Christopher, Advanced Drug Delivery Reviews, 9 (1992), pp. 119-135, "What are the pathways of iontophoretic current flow through mammalian skin?".
Hirvonen, J., et al., Proceed, Intern. Symp. Control. Rel. Bioact. Mater., 19 (1992), Controlled Release Society, Inc., pp. 452-453, "Transdermal Permeation of Model Anions and Cations; Effect of Skin Charge, Iontophoresis and Penetration Enhancers".
Del Terzo, Sam, et al., Pharmaceutical Research, Col. 6, No. 1, 1989, pp. 85-90, "Iontophoretic Transport of a Homologous Series of Ionized and Nonionized Model Compounds: Influence of Hydrophobicity and Mechanistic Interpretation".
Ferber, et al., Abstract: Pharmaceutical Research, Sep. 1990 (Suppl.), vol. 7, No. 9, PDD 7256, "Alkanol Enhancement of Transdermal Penetration of Water Soluble Compounds".
Indian J. Pharm. Sci., vol. 56, No. 6, Nov. 1994 pp. 205-209, XP 000563597, Chandrasekar, G.; et al, "Optimization of Parameters for Trannsdermal Permeation of Insulin".
Barry, B.W., Journal of Controlled Release, 6 (1987) pp. 85-97, "Mode of Action of Penetration Enhancers in Human Skin.".
Behl, et al., Journal of Pharmaceutical Sciences, vol. 78, No. 5, (1989) pp. 355-360, "Iontophoretic Drug delivery: Effects of Physicochemical Factors on the Skin Uptake of Nonpeptide Drugs."

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for enhanced electrotransport agent delivery does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for enhanced electrotransport agent delivery, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for enhanced electrotransport agent delivery will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1247165

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.