Coating processes – Medical or dental purpose product; parts; subcombinations;... – Particulate or unit-dosage-article base
Patent
1996-10-18
2000-06-13
Beck, Shrive
Coating processes
Medical or dental purpose product; parts; subcombinations;...
Particulate or unit-dosage-article base
427 8, 427458, 427466, 427475, B05D 106, B05D 314
Patent
active
060746882
ABSTRACT:
Method for electrostatically depositing select doses of medicament powder at select locations on a substrate. Specifically, the apparatus contains a charged particle emitter for generating charged particles that charge a predefined region of a substrate and a charge accumulation control circuit for computing the amount of charge accumulated upon the substrate and deactivating the emitter when a selected quantity of charge has accumulated. Additionally, a triboelectric charging apparatus charges the medicament powder and forms a charged medicament cloud proximate the charged region of the substrate. The medicament particles within the medicament cloud electrostatically adhere to the charged region. The quantity of charge accumulated on the substrate at the predefined region and the charge-to-mass ratio of the medicament powder in the cloud control the amount (dose) of medicament deposited and retained by the substrate. Consequently, this apparatus accurately controls both medicament dosage and deposition location. Furthermore, since the substrate can be of any dielectric material that retains an electrostatic charge, the apparatus can be used to deposit medicament on substrates that are presently used in oral medicament consumption, e.g., substrates that are used to fabricate suppositories, inhalants, tablets, capsules and the like.
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Datta Pabitra
McCoy Randall Eugene
Pletcher Timothy Allen
Poux Christopher Just
Beck Shrive
Delsys Pharmaceautical Corporation
Parker Fred J.
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