Method for electrochemiluminescent labeling of nucleic acid, use

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 911, 435 915, 436501, 536 221, 536 253, 536 2532, 935 77, 935 78, C12Q 168

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060278854

ABSTRACT:
Method for immobilizing nucleic acids by hybridizing the nucleic acid with a capture probe. The capture probe is protected against enzymatic extension and/or enzymatic degradation of the formed hybrid.

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patent: 5487972 (1996-01-01), Gelfand et al.
"Enzymatic synthesis of biotin-labeled polynucleotides: Novel nucleic acid affinity probes" Biochemistry: Langer et al, Proc. Natl. Acad. Sci USA 78 (1981 pp. 6634-6637.
Iribarren et al, Proc. Natl. Acad. Sci. USA 87, 7747-7751 (1990).
Holland et al, Proc. Natl. Acad. Sci. USA 88, 7276-7280 (1991).

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