Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1996-12-20
2000-02-22
Marschel, Ardin H.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 435 915, 436501, 536 221, 536 253, 536 2532, 935 77, 935 78, C12Q 168
Patent
active
060278854
ABSTRACT:
Method for immobilizing nucleic acids by hybridizing the nucleic acid with a capture probe. The capture probe is protected against enzymatic extension and/or enzymatic degradation of the formed hybrid.
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patent: 5487972 (1996-01-01), Gelfand et al.
"Enzymatic synthesis of biotin-labeled polynucleotides: Novel nucleic acid affinity probes" Biochemistry: Langer et al, Proc. Natl. Acad. Sci USA 78 (1981 pp. 6634-6637.
Iribarren et al, Proc. Natl. Acad. Sci. USA 87, 7747-7751 (1990).
Holland et al, Proc. Natl. Acad. Sci. USA 88, 7276-7280 (1991).
Berner Sibylle
Kaletta Cortina
Kruse-Mueller Cornelia
Marschel Ardin H.
Roche Diagnostics GmbH
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